Hitmen Jules Winnfield and Vincent Vega arrive at an apartment to retrieve a briefcase for their boss, gangster Marsellus Wallace, from a business partner, Brett. After Vincent checks the contents of the briefcase, Jules shoots one of Brett’s associates. He declaims a passage from the Bible, and he and Vincent kill Brett for trying to double-cross Marsellus. They take the briefcase to Marsellus and wait while he bribes boxer Butch Coolidge to take a dive in his upcoming match.
The next day, Vincent purchases heroin from his drug dealer, Lance. He shoots up and drives to meet Marsellus’s wife Mia, having agreed to escort her while Marsellus is out of town. They eat at Jack Rabbit Slim’s, a 1950s-themed restaurant, and participate in a twist contest, then return home. While Vincent is in the bathroom, Mia finds his heroin and snorts it, mistaking it for cocaine. She suffers an overdose; Vincent rushes her to Lance’s house, where they revive her with an injection of adrenaline into her heart. Vincent drops Mia off at her home, and the two agree never to tell Marsellus about the incident.
Butch bets the bribe money on himself and double-crosses Marsellus, winning the bout but accidentally killing his opponent as well. Knowing that Marsellus will send hitmen after him, he prepares to flee with his girlfriend Fabienne, but discovers she has forgotten to pack a gold watch passed down to him through his family. Returning to his apartment to retrieve it, he notices a submachine gun on the kitchen counter and hears the toilet flush. When Vincent exits the bathroom, Butch shoots him dead and departs.
When Marsellus spots Butch stopped at a traffic light, Butch rams his car into him, leaving both of them injured and dazed. Once Marsellus regains consciousness, he draws a gun and shoots at Butch, chasing him into a pawnshop. As Butch gains the upper hand and is about to shoot Marsellus, Maynard the shop owner captures them at gunpoint and binds and gags them in the basement. Maynard and his accomplice Zed take Marsellus into another room and begin to rape him, leaving the “gimp” – a silent figure in a bondage suit – to watch over Butch. Butch breaks loose and knocks the gimp unconscious. Instead of fleeing, he decides to save Marsellus, and arms himself with a katana from the pawnshop. He kills Maynard and frees Marsellus, who shoots Zed in the crotch with Maynard’s shotgun. Marsellus informs Butch that they are even, and to tell no one about the rape and to depart Los Angeles forever. Butch picks up Fabienne on Zed’s chopper, and they drive away.