Discuss pharmacology of existing agents briefly, molecular mechanism of action, therapeutic & adverse effects, & relevant kinetics, all as short paragraphs, readable

 

What are the major adverse effects of Statins (muscle related), Hydralazine (many, lupus like syndrome), and glipizide (hypoglycemia) HCTZ (hypokalemia). 2022 latest answers

 

Why can’t this patient be a candidate for metformin, the best used diabetes drug, efficacious, no hypoglycemic attacks?