How does the O-helix function to facilitate DNA replication?   2022 latest answers

  Regarding proofreading:

a. How often are bases misincorporated by DNA polymerase?

b. What is the difference between a 3’→5’ exonuclease and 5’→3’ exonuclease?

c. How does DNA polymerase’s proofreading domain detect and remove misincorporated bases?

d. What is the error rate of DNA synthesis?