Advanced Pharmacology Subscribe Opioid overuse is a significant problem in the United States and abroad. According to Covvey 2015, hydrocodone is one of the most prescribed and widely abused schedule II drugs, contributing to the opioid epidemic. Prolonged use of opioid medication is also associated with increased mortality rate due to overdose. Chronic pain can play a role in patient dependency on narcotic medications; frequent evaluation of pain and patient medication management should be considered with prescribing various scheduled drugs. In the case study, it is evident that the patient has developed a dependency on the medication, or her pain is not being appropriately managed. Upon assessment, the current medication regimen should be changed to an extended-release drug and maybe incorporate a non-narcotic along with non-pharmacological methods.The determined conversion reduced by 25% ?for hydrocodone APAP 10/325 to morphine ER 7.5 mg daily every 4-6 hours. According to Seago 2016, research conducted identified no change in patient behavior of users in the prescription drug when?changed to morphine with a federal recommendation to change,?reduction in Norco (Hydrocodone) 10/325, and no statistically significant change in morphine sulfate.

 Alternative medicine may offer relief with combination therapy; however, this method of treatment if often frowned upon due to lack of research. The use of non-pharmacologic modalities has been questioned by medical practitioners because of the perceived lack of prospective, randomized, double-blind sham-controlled studies supporting their use in clinical practice (White et al., 2017). A few alternative therapies that may be used along with medication for this patient may include Electroanalgesia is a form of neuromodulation therapy, percutaneous electrical nerve stimulation (PENS), or transcutaneous electrical nerve stimulation (TENS). In addition to changing the opioid, it may also be beneficial to prescribe a non-opioid break-through medication to ensure the patient does not have any acute pain due to a change of medication. ? Migraine headaches are characterized by the attacks of unilateral, throbbing head pain, with sensitivity to movement, visual, auditory, and other afferents inputs?(Goadsby et al., 2017). In this case, CM is also experiencing?difficulty sleeping and is mildly anxious; these symptoms could be a result of her post migraine symptoms that can cause fatigue and anxiousness days to months post the migraine. Her medication options include drug therapy that is not contraindicated with inhaler use.

 Non-pharmacologic treatment for migraine management, which could consist of avoiding triggers such as audio, visual, movements, and stress. CM could also darken the room, apply ice to the neck area, drink a caffeinated beverage, and improve sleep. She should also maintain a diary to keep track of the frequency and triggers association with her headaches. Prophylaxis migraine treatment may be an option; however, per the literature, the practice is more familiar with chronic migraine patients.?Prophylactic migraine treatment should be considered if more than three migraine headaches per month or eight headache days in one month, in severe debilitating headaches despite appropriate acute treatment, intolerant, or have contraindications to acute therapy (Kumar & Kadian, 2020). ? ? Reference Covvey J. R. (2015). Recent developments toward the safer use of opioids, with a focus on hydrocodone.?Research in social & administrative pharmacy : RSAP,?11(6), 901?908. ? Kumar, A. & Kadian, R. (2020 Aug 15). Migraine prophylaxis.?StatPearls. Retrieved from: ? Seago, S., Hayek, A., Pruszynski, J., & Newman, M. G. (2016). Change in prescription habits after federal rescheduling of hydrocodone combination products.?Proceedings (Baylor University. Medical Center),?29(3), 268?270. less 0 Unread 0 Unread 5 Replies 5 Replies 23 Views 23 Views View profile card for Kelly Miskovsky Last post?Oct 15, 2020 9:39 AM?by Kelly Miskovsky Module V: Pain Management Discussion ?

 Must post first. Subscribe There are hundreds of opioid conversion calculators available online, though they are not all of good quality.? I would like to direct you to one of the opioid conversion calculators that I find to be most useful and evidence based.? Locate? evaluate the following case using the calculator as necessary. Discuss your approach to the overall case and results of your calculation. A 79 year old white male is taking hydrocodone/APAP 10/325 for lower back pain (pt diagnosed with degenerative disc disease several months ago). The physician had written a prescription for?Vicodin? 10/325? i-ii Q4-6h prn pain with a quantity of 120.? Her expectation was that this would last the patient for one month.? The patient is now requesting refills about every 10-14 days.? He states he has been taking 2 tabs Q4h (12 tablets per day) because ?the pain is so bad I just can?t stand it!?. What is the problem with the way the patient is taking this medication versus the way it was prescribed Based on your assessment, it is determined this patient should be converted to extended release morphine for better, more consistent pain control. Perform this conversion and provide an appropriate recommendation (drug, dose, frequency). 

Migraine is a major neurological disease that affects more than 36 million men, women and children in the United States. There is no cure for migraine. Most current treatments aim to reduce headache frequency and stop individual headaches when they occur.?Let?s look at a case example: CM is 20 years old female with severe, prolonged 2 to 3 day migraines twice per month. She has difficulty sleeping and is mildly anxious. She occasionally utilizes an inhaler for asthma. Provide an evaluation of CM?s condition including non-pharmacological interventions?and treatment options Is Cm a candidate for prophylactic therapy, and if so, what option would be best suited to her? Post your initial response by Wednesday at midnight. Respond to one student by Sunday at midnight.? Both responses should be a minimum of 150 words, scholarly written, APA formatted, and referenced.? A minimum of 2 references are required (other than your text). Refer to the Grading Rubric for Online Discussion in the Course Resource section.?

 Feedback 88 / 100 View Graded Rubric Start a New Thread Discussion Filter by: All Threads Sort by: Most Recent ActivityLeast Recent ActivityNewest ThreadOldest ThreadAuthor First Name A-ZAuthor First Name Z-AAuthor Last Name A-ZAuthor Last Name Z-ASubject A-ZSubject Z-A Module V ? Pawn Johnson-Hunter posted Oct 1, 2020 1:59 AM Module V ? Shante Hunt posted Sep 30, 2020 7:10 PM Subscribe The first patient is a 79 year old male who has been prescribed hydrocodone/APAP 10/325 for lower back pain.??The directions on his prescription is to take one to two tablets every four to six hours as needed for pain, and the patient reports that he is taking two tablets every four hours, or twelve pills per day for severe pain.??Based on this information, the patient is taking a total daily dose of 120 mg of hydrocodone.??When converting hydrocodone to extended release morphine, or MS Contin using the standard MME dosage conversion (, the patient should receive 120 mg of equianalgesic however to decrease the risk of sedation I have chosen to lower the dose by 25%??for a total daily dose of MS Contin 90 mg daily divided in 3 doses.??Decreasing the dose by this amount is done to prevent overdose and to allow for incomplete cross tolerance that can occur when switching from one opioid to another (, 2018).?

?Another motivating factor to discontinue the use of Vicodin is that this patient is also consuming 3,900 mg of acetaminophen daily and while that is just below the daily allowance of 4,000 mg, caution should be exercised in this patient due to his age and potential for decreased renal function.??This patient has been taking this medication on a scheduled basis rather than as needed so it is clear that his pain is not well managed using Vicodin.??Mehalick et al (2016) demonstrated that the use of opioid pain medication versus the use of combination non-opioid/opioid medications for treatment of low back pain did not demonstrate a significant difference in reports of pain levels, either increase or decrease.??Therefore, it is clinically beneficial to eliminate acetaminophen in this case as he may increase the frequency of administration on his own. ? CM is a 20 year old female who reports symptoms associated with acute migraine headaches that are severe in nature.??Initial treatment of mild to moderate migraines should begin with NSAIDs, however since CM reports her symptoms as severe she meets criteria for a migraine specific medication such as Sumatriptan 25 mg by mouth, with instructions to repeat the dose if no effect in two hours (MacGregor, 2017

).??This medication can also be given intranasally if nausea presents and CM cannot tolerate anything by mouth, but it is also more rapidly absorbed and provides faster relief of symptoms.??Non-pharmacological treatment of migraines should include a comprehensive review of CM?s diet and suggested dietary changes to avoid caffeine, artificial sweeteners and MSG (MacGregor, 2017).??A full assessment of triggers and timing can indicate whether the attacks are as a result of hormonal changes in the menstrual cycle and whether or not an aura exists.??Since CM?s attacks do not follow a specific pattern, nor does she have fifteen or more attacks per month, I would not recommend prophylactic treatment for her, rather I would follow her closely to determine if increased doses of acute medications are warranted. ? Centers for Disease Control and Prevention. (2018).?CDC guidelines for prescribing opioids for chronic pain.? ? MacGregor, E.A. (2017). In the clinic. Migraine.?Annals of Internal Medicine, 159(9), 1-16. Doi: 10.7326/AITC201704040 Mehalick, M., McPherson, S., Schmaling, K., Blume, A., & Magnan, R. (2016). Pharmacological management of chronic low back pain: A clinical assessment.?Journal of Pain Management, 9(1), 39-48.? less 0 Unread 0 Unread 3 Replies 3 Replies 17 Views 17 Views View profile card for Kelly Miskovsky Last post?Oct 15, 2020 9:35 AM?by Kelly Miskovsky Module 5 ? Anna McMullen posted Sep 28, 2020 4:41 PM Subscribe ? less 0 Unread 0 Unread 2 Replies 2 Replies 12 Views 12 Views View profile card for Pawn Johnson-Hunter Last post?Oct 4, 2020 9:18 PM?by Pawn Johnson-Hunter Module V Pain Management ? Gisselle Mustiga posted Oct 1, 2020 12:52 AM Subscribed Pain Management Hydrocodone is an opiate often used in a combination with other substances as a pain reliever (Chisholm-Burns et al., 2016). The drug works by altering the brain?s perception of pain. The problem with the drug is consumption against how they were prescribed is the risk of an overdose. This surplus consumption of hydrocodone occurs due to the addictive factors of the medication. An overdose is observable from symptoms like slowed heartbeats, sleepiness, seizures, shallow breathing, narrow pupils, or death in worst scenarios. 

The conversion process encompassed analyzing the amount of morphine relative to the opioid quantity. The physician recommended Vicodin 10/325 Q4- 6h prn. Since the quantity was 120 for 30 days, the patient was to take four tablets daily. Upon the conversion with a percentage reduction of 25%, the victim ought to receive a morphine dose of 30mg every four to six hours (Practical Pain Management, 2020). The new dosage is attributable to the patient increasing their dosage to 12 tablets a day. Migraines Migraines are neurological mishaps that cause headaches among individuals (Puledda & Shields, 2018). Its situation becomes worse when pharmacological remedies are insufficient in pain management. Healthcare professional often recommends non-drug methods like nutraceuticals, behavioral modifications, noninvasive neuromodulation, and invasive modulation. The first mechanism centralizes on employing food supplements to enhance one?s health and control of migraines. The second technique comprises of actions meant to deter the dire consequences of the condition by relaxing the one?s cognitive muscles. 

The last two methods are advisable for individuals with chronic migraines (Rokyta & Fricova, 2014). Both processes involve nerve stimulation. I believe CM is a suitable patient for prophylactic therapy due to the severity of her migraines. According to Modi and Lowder (2006), she is best suited to utilize Topiramate, a first-line agent in migraine control. Such medication would mitigate the losses she faces due to her condition by advancing her life quality and thus making her more productive. References Chisholm-Burns, M. A., Wells, B. G., & Schwinghammer, T. L. (2016).?Pharmacotherapy principles and practice. McGraw-Hill. Modi, S., & Lowder, D. M. (2006). Medications for migraine prophylaxis.?American family physician,?73(1), 72-78. Practical Pain Management. (2020).?Opioid Calculator. Puledda, F., & Shields, K. (2018). Non-pharmacological approaches for migraine.?Neurotherapeutics,?15(2), 336-345. Rokyta, R., & Fricova, J. (2014).

 Noninvasive neuromodulation methods in the treatment of chronic pain.?Pain and Treatment. London: IntechOpen Limited, 175-190. less 0 Unread 0 Unread 2 Replies 2 Replies 24 Views 24 Views View profile card for Anna McMullen Last post?Oct 4, 2020 11:45 AM?by Anna McMullen Module V: Pain Management ? Jessica Faltinowski posted Sep 30, 2020 3:57 PM Subscribe Module V:? Pain Management When starting opioid therapy for a patient after non-opioid therapies have been used, the patient should be started on a short acting drug at the lowest dose possible.? In our case study, the patient was taking the short acting opioid at the maximum dosage around the clock, instead of using it when the pain was in the moderately severe to severe range, as prescribed.? When taking a pain medication in a way not indicated, the patient can develop a tolerance to the opioid and require a stronger dose to achieve pain control. As degenerative disc disease is a chronic pathology, this patient will continue to experience pain and requires multifocal pharmacological management.? The hydrocodone ordered for the patient was ordered with a maximum dosage of between 40 mg (if the patient took 10 mg hydrocodone every 6 hours) and 120 mg (taking 20 mg every 6 hours).? As the patient is already taking the maximum dosage, an extended release equivalent dose would be more effective.? The conversion of our patient?s hydrocodone dose to oxycodone, a pure agonist opioid, would be a maximum dosage (which is the current amount the patient is taking) of 80 mg per day (Brennan et al., 2020) dosed as 40 mg every 12 hours

. The medication could be written for oxycodone 20 mg 1-2 pills every 12 hours as needed for severe pain with education provided to the patient to start with the lowest dose. A prescriber needs to be noticeably clear when prescribing these medications and ensure the patient understands how it is being written and signs an opioid contract for how they would take it (Dowell et al., 2016).? Another appropriate intervention would be to refer the patient to a pain clinic as they have additional therapies available, in addition to trained addiction therapists and doctors. However, all providers must be aware of the drawbacks of opioid therapy and their potential for abuse.? In the elderly population, usage of oxycodone shows a significantly greater incidence of respiratory depression (Kinnunen et al., 2019).

? As such, our patient must also be prescribed naloxone, an opioid antagonist, and he and other family members must be educated on how and when to use it (Chimbar, 2018). At some point in their lives most people experience headaches.? However, it is important to be able to distinguish a typical headache from a more severe headache such as a migraine, cluster headache, or tension related headache.? Migraine headaches have an unclear etiology but activation of the trigeminovascular pathways resulting in an imbalance in serotonergic and noradrenergic neurons is a widely accepted pathology (Goadsby et al., 2017).? Migraine headache symptoms include a unilateral pulsatile or throbbing pain indicated in the moderate to severe category, along with photosensitivity, nausea, and vomiting (Goadsby et al., 2017).? Migraines tend to effect females three times as often as men.? Research suggests that approximately 38% of those with episodic migraines would be benefitted by prophylactic treatment, however only 3-13% utilize it (Ha & Gonzalez, 2019, p. 17). CM is endorsing severe, prolonged headaches lasting 2-3 days each, at a frequency of twice monthly.? Additional symptomatology indicates mild anxiety and difficulty sleeping.?

 In order to evaluate triggers to migraines, CM will be encouraged to keep a headache diary for 30 days in which she documents headache quality, intensity, length of time, other symptoms such as nausea and vomiting, whether or not she experienced aura, food she consumed, medications she took, her menstrual cycle, and the daily weather.? If CMs neurological examination is normal and she does not have any red flags such as seizures or swelling of her optic nerve, then an imaging study is not indicated (Charles, 2017).? A ?complete medication history will also be obtained, as some medications, such as oral contraceptives, proton-pump inhibitors, and selective serotonin-reuptake inhibitors can exacerbate migraines (Ha & Gonzalez, 2019). Most providers agree that preventative therapy should be initiated when migraines occur at least once per week or for 4 or more days per month (Charles, 2017).? CM will be provided with a serotonin receptor agonist, commonly referred to as a triptan, such as sumatriptan or zolmitriptan, to take at the onset of a migraine (Ha & Gonzalez, 2019).? After CM completes her headache diary, it can be analyzed to determine the best prophylactic therapy.?

 First-line prophylactics for migraines include beta blockers such as propranolol, anticonvulsants such as valproic acid, antiepileptic such as topiramate, and tricyclic antidepressants such as amitriptyline (Ha & Gonzalez, 2019).? Venlafaxine has also been used as a prophylactic with good results.? Venlafaxine?s mechanism of action is to decrease 5-HT levels which affect development of vestibular symptoms (Liu et al., 2017). ?As CM uses an inhaler for asthma, beta blockers such as propranolol would not be a good first line option for her, but instead topiramate or venlafaxine would be considerations.? Since CM also endorses mild anxiety, venlafaxine would be a good first line therapy for her.? Studies show that venlafaxine decreases the number of migraine attacks per month significantly, in addition to decreasing their length and severity (Ha & Gonzalez, 2019).? CM will have the maximum benefit in combination therapy, utilizing cognitive behavior therapy and relaxation therapy along with her medication. References Brennan, M., Fudin, J., & Perkins, R. (2020).?Practical pain management. Opioid calculator. Retrieved September 30, 2020, from? Charles, A. (2017). Migraine.?New England Journal of Medicine,?377(6), 553?561.? Chimbar, L. (2018). Naloxone effectiveness: A systematic review.?Journal of Addictions Nursing,?29(3), 161?171.? Dowell, D., Haegerich, T. M., & Chou, R. (2016). Cdc guideline for prescribing opioids for chronic pain?united states, 2016.?JAMA,?315(15), 1624.? Goadsby, P. J., Holland, P. R., Martins-Oliveira, M., Hoffmann, J., Schankin, C., & Akerman, S. (2017). Pathophysiology of migraine: A disorder of sensory processing.?Physiological Reviews,?97(2), 553?622.? Ha, H., & Gonzalez, A. (2019). Migraine headache prophylaxis.?American Family Physician,?99(1), 17?24. Kinnunen, M., Piirainen, P., Kokki, H., Lammi, P., & Kokki, M. (2019). Updated clinical pharmacokinetics and pharmacodynamics of oxycodone.?Clinical Pharmacokinetics,?58(6), 705?725.? Liu, F., Ma, T., Che, X., Wang, Q., & Yu, S. (2017). The efficacy of venlafaxine, flunarizine, and valproic acid in the prophylaxis of vestibular migraine.?Frontiers in Neurology,?8.? less 0 Unread 0 Unread 2 Replies 2 Replies 17 Views 17 Views View profile card for Kathryn Mosholder Last post?Oct 4, 2020 11:00 AM?by Kathryn Mosholder Module V pain management discussion ? Robin Morgan posted Sep 28, 2020 9:26 PM Subscribe Module V discussion Advanced Pharmacology Prescription opioids are powerful pain-reducing medications that have both benefits as well as potentially serious risks. 

The addiction rates of opioids continue to rise, despite the FDA?s efforts to regulate and control their use. As healthcare professionals we must be educated on properly managing these highly addictive drugs. Opioids must be appropriately indicated for the patient that it is being prescribed and only at doses and durations that match the clinical reason the drug is being prescribed. Due to the highly addictive nature of opioids our case study patient a 79-year-old male should take his Vicodin only as prescribed. This patient has been taking 12 tables of Vicodin per day, the maximum dose of Vicodin 10mg/300mg is 8 tables(Caldwell et al., 2019). This medication can become habit forming and also contains acetaminophen that can be toxic to onus?s liver. Do to the fact that our patient is not getting relief from the Vicodin as prescribed, the next course of action would be a long acting pain medication such as morphine ER. Utilizing the opioid calculator to determine the converting dose from hydrocodone to morphine ER, I would change this patient to morphine ER 45mg every twelve hours reducing calculation by 25% to give room for incomplete tolerance. Chronic migraines have been shown to be a greater burden on life than other headache conditions.

Migraines can interfere with your life, causing missed work and taking time away from one?s family. The key is attempting to prevent migraines from even starting, because taking acute mediations too often can lead to medication overuse headache conditions(Perlman & Weisman, n.d.). CM is a 20-year-old female who is seeking treatments for migraines, Since CM has difficulty sleeping and mild anxiety, I would suggest she tried to improve sleeping habits. Establish regular sleep hours, unwind at the end of the day by having a warm bath or listening to soothing music, and avoiding caffeine at the end of the day. I would offer CM some tips to manage stress time management, relax, try doing something special for herself at least 15 minutes per day. Other ways she could prevent migraines is eating healthy, getting regular exercise, keeping a migraine diary to look for triggers to avoid. Often times inhalers have the side effect of causing headaches, so controlling asthma and the need for inhalers may help CM, or reducing the dose of possible.

 CM would be a good candidate for prophylactic treatment of migraines my first line drug of choice would be amitriptyline, this medication could help to prevent migraines as well as help with CM?s mild anxiety. References Caldwell, W. K., Freedman, B., Settles, L., Thomas, M. M., Camacho, E. T., & Wirkus, S. (2019). The vicodin abuse problem: A mathematical approach.?Journal of Theoretical Biology,?483, 110003.? Perlman, A., & Weisman, R. (n.d.).?Own your health: Pain: Back pain, arthritis, migranes, joint pain, and more. Health Communications, Incorporated. ? ? less 0 Unread 0 Unread 1 Replies 1 Replies 11 Views 11 Views View profile card for Augusta Ibeh Last post?Oct 2, 2020 11:20 PM?by Augusta Ibeh Module V discussion ? Augusta Ibeh posted Oct 1, 2020 12:16 AM Subscribe Pain management, which affects approximately 25.3 million adults nationwide,1?can be a difficult and frustrating experience Haverfield et al. (2018).

 Patients and providers have different views on making decision about pain. Clinicians report difficulty in prescribing opioids and trusting their clients pain reports, clients also feel that the clinicians are not listening to their problems Haverfield et al. (2018). Patient-centered care defines the clinician?s attentiveness to the clients care preferences and need. Patients should be involved in their care; communication is the best tools that will help to satisfy and meet patient?s care. Opioids are the most potent drugs producing analgesia and is used in the treatments both acute and chronic pain. The largest part of prescriptions regarding opioids are oxycodone, hydrocodone, morphine, codeine, methadone and transdermal morphine and fentanyl Cardia et al. (2018). Currently, patient is taking Hydrocodone 10/325 at a rate of 120 MME per day total.

 The conflict is the maximum MME prescribed is 60 MME per day total, but the patient is taking the prescribed medicine at double the dosage prescribed by the doctor. Changing the prescription to Morphine ER 15-20 mg orally based on the conversion scheduled, it will be recommended the patient takes one tablet every 12 hours and a breakthrough pain relieved with Ibuprofen 600mg if not contracted. PATIENT CALCULATION: [10 mg] *[12 tablets] = 120 mg Vicodin/day?à?[120 mg Vicodin] *[1] = 120 MME per day total PRESCRIBED CALCULATION: [10 mg] *[6 tablets] = 60 mg Vicodin/day?à?[60 mg Vicodin] *[1] = 60 MME per day total NEW PRESCRIPITON: [20 mg] *[2 tablets] = 40 mg Morphine/day?à?[40 mg Morphine] *[1] = 40 MME per day total ? Migraine is a chronic neurologic disease that varies in its frequency, severity, and impact on patients? quality of life.?Migraine treatment for CM should be based on the diagnosis, symptoms, and coexistent or comorbid conditions and her expectations, needs and goals to improve quality life?Silberstein (2015).

 American Academy of Neurology?s evidence-based guidelines for clinicians). These guidelines include: ?Recurring migraine attacks that significantly interfere with a patient?s quality of life and daily routine despite trigger management, appropriate use of acute medications, and lifestyle modification strategies Frequent headaches (four or more attacks per month or eight or more headache days per month) because of the risk of chronic migraine Failure of, contraindication to, overuse of, or troublesome side effects from acute medications Patient preference, that is, the desire to have as few acute attacks as possible Presence of certain migraine conditions: hemiplegic migraine; basilar migraine (now called migraine with brainstem aura); frequent, prolonged, or uncomfortable aura symptoms; or migrainous infarction?Silberstein (2015).????? Preventive treatments can be preemptive, short term or maintenance. Preemptive treatment is used when headache triggers migraine such, exercise or sexual activities. Patient is asked to take prescribed medication for migraine before the activity. Patient can benefit from topiramate 15 mg at bedtime and the dose titrated to 50 mg twice daily for over a course of 6 weeks Silberstein (2015)

. Usually there is a reduction of headache days per month and the reduction of duration of attacks for less than 60 minutes after taking sumatriptan 100 mg Silberstein (2015). Other medications that can be used is Ibuprofen 600 mg for other attacks. Reference Cardia, L., Calapai, G., Quattrone, D., Mondello, C., Arcoraci, V., Calapai, F., Mannucci, C., & ? Mondello, ??????????? E. (2018). Preclinical and Clinical Pharmacology of Hydrocodone for ?????? Chronic Pain: A Mini ??????????? Review.?Frontiers in pharmacology,?9, 1122. ?????????? Haverfield, M. C., Giannitrapani, K., Timko, C., & Lorenz, K. (2018). Patient-Centered Pain ???? Management Communication from the Patient Perspective.?Journal of general internal ? medicine,?33(8), 1374?1380. Opioid Calculator. (n.d.). Retrieved from Silberstein?S. D. (2015). Preventive Migraine Treatment.?Continuum (Minneapolis, Minn.),?21(4 Headache), 973?989. less 0 Unread 0 Unread 3 Replies 3 Replies 28 Views 28 Views View profile card for Kelly Miskovsky Last post?Oct 2, 2020 3:43 PM?by Kelly Miskovsky Pain Management ? Kathryn Mosholder posted Sep 30, 2020 11:46 PM Subscribe The first case scenario is a 79 yr old male with severe back pain due to degenerative disc disease diagnosed several months ago. He is currently taking hydrocodone/APAP 10/325mg for pain. His provider prescribed 120 pills for him to take q 4 to 6 hours for 30 days. He takes as many as 12 tabs a day instead of the specified amount of up to 4 pills a day. He states the reason he is taking two tabs every four hours is due to the pain is so bad he can?t tolerate it. 

The problem with the way this patient is taking his medication is the fact that he is taking double the amount of hydrocodone recommended for a 24 hr. period. He is taking up to 120mg of hydrocodone when the recommended max dose is 60mg in a 24 hr. period. Instead of taking his medication as needed, he is taking it scheduled, which Vicodin is not a recommended scheduled medication. The problem with pain medication for older patients is they are more prone to adverse outcomes such as disruption of sleep, falls, and depression (Zis et al., 2017). First, a full pain assessment and x-rays before routine pain regiment is prescribed (Zis et al., 2017). However, morphine extended-release would be acceptable. I would attempt topical lidocaine patches and Voltaren gel, and orthopedics consult for a possible injection before going straight to pain medication. I would recommend morphine extended-release as my last resort due to his age and diagnosis. The second case scenario is a twenty-year-old female with two to three-day migraines twice per month.

 She is having difficulty sleeping and is mildly anxious. Migraines are among the most common somatic complaints among children and young adults (Andersson et al., 2017). Due to the prevalence of migraines in young adults, many patients try to self-treat when they become frustrated with other prescribed methods (Andersson et al., 2017). Young adults with migraines or cluster headaches are at high risk for suicide due to pain and frustration and illegal drug use that they may be trying to self treat due to other failed methods (Andersson et al., 2017). With this patient, I would do a full pain assessment and neurological assessment before prescribing migraine medication (Andersson et al., 2017). Additionally, the goal is to provide treatment for headache day and prevent future headaches. Many migraine medications have drug interactions with other medicines, so a full history of drugs and diseases is essential before writing scripts. Providing she has no other conditions, I would recommend Topamax 25 mg/day to start as a preventative medication and Sumatriptan nasal spray 5mg for a PRN on the go medication (Andersson et al., 2017).